Fragile X Mental Retardation Protein

Fragile X Mental Retardation Protein In Learning- Related ...
Fragile X mental retardation protein controls mGluR-dependent long-term depression. Neuron 51, 441-454. Hu, H., Qin, Y., Bochorishvili, G., Zhu, Y., van Aelst, L., and Zhu, J.J. (2008). Ras signaling mechanisms underlying impaired GluR1- ... Access Content

Brain Plasticity In The Context Of fragile X-syndrome ...
My lab has extensively studied the molecular basis of the Fragile X Syndrome (FXS), which is caused by the absence of the Fragile X Mental Retardation Protein, FMRP. FMRP is implicated in mRNA metabolism at synapses, and the study of the protein and of its mRNA offers a major inroad ... View Video

Molecular Cell Article - Researchgate.net
Molecular Cell Article Fragile X Mental Retardation Protein Regulates Translation by Binding Directly to the Ribosome Eileen Chen,1,4 Manjuli R. Sharma,2,4 Xinying Shi,1 Rajendra K. Agrawal,2,3,* and Simpson Joseph1,* ... Retrieve Content

Fragile X Mental Retardation Protein Expression In Alzheimer ...
ORIGINAL RESEARCH ARTICLE published: 21 October 2014 doi: 10.3389/fgene.2014.00360 Fragile X mental retardation protein expression in Alzheimer’s disease ... Return Doc

Fragile X Mental Retardation Protein Modulates The Fate Of ...
Fragile X mental retardation protein modulates the fate of germline stem cells in Drosophila Lele Yang1,{, Ranhui Duan2,{, Dongsheng Chen1,3, Jun Wang1, Dahua Chen1,* and Peng Jin2,* ... Document Retrieval

Fragile X Mental Retardation Protein: From Autism To ...
OPINION ARTICLE published: 12 February 2015 doi: 10.3389/fncel.2015.00043 Fragile X mental retardation protein: from autism to neurodegenerative disease ... Fetch Full Source

Fragile X Mental Retardation Protein Is - JSTOR
Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses Ivan Jeanne Weiler*tt, Chad C. Spangler*t, Anna Y. Klintsova*, Aaron W. Grossman*?, Soong Ho Kim*?, ... Get Document

Dysregulation Of fragile X Mental Retardation Protein And ...
Dysregulation of fragile X mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study S Hossein Fatemi1,2,3* and Timothy D Folsom1 Abstract ... Return Document

Chromosome Mutation - About.com Education
A chromosome mutation causes changes in the structure or number of chromosomes in a cell. These mutations are often caused by errors that occur during the process of cell division or by mutagens. These changes affect protein production by changing the genes on the chromosome. ... Read Article

Fragile X Mental Retardation Protein Deficiency Leads To ...
Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors Mika Nakamoto*, Vijayalaxmi Nalavadi†, Michael P. Epstein*, Usha Narayanan*, Gary J. Bassell† ... Doc Retrieval

Fragile X Mental Retardation Protein Is Necessary For ...
Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses Ivan Jeanne Weiler*†‡, Chad C. Spangler*†, Anna Y. Klintsova*, Aaron W. Grossman*§, Soong Ho Kim*§ ... Document Retrieval

Original Article Regulation Of GABA Receptors By fragile X ...
Regulation of GABA A receptors by fragile X mental retardation protein 174 Int J Physiol Pathophysiol Pharmacol 2013;5(3):169-176 Figure 4. FMRP inhibits GABA ... Retrieve Content

FXR2 - Wikipedia, The Free Encyclopedia
Fragile X mental retardation syndrome-related protein 2 is a protein that in humans is encoded by the FXR2 gene. [1] [2] [3] The protein encoded by this gene is an RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. ... Read Article

Fragile X Mental Retardation Protein In The Driver’s Seat
Fragile X Mental Retardation Protein in the Driver’s Seat Jay E. Brenman Department of Cell and Developmental Biology and Neuroscience Center, UNC Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA Keywords: autism, FMRP, fmr1, Fragile X, GABA, mental retardation, ... View This Document

Chapter 8 Fragile X Mental Retardation Protein And Stem Cells
Chapter 8 Fragile X Mental Retardation Protein and Stem Cells Abrar Qurashi, Xuekun Li, and Peng Jin Abstract Stem cells, which can self-renew and produce different cell types, are ... Fetch Document

Phenylketonuria (PKU) - Inherited Metabolic Disorder
An overview of phenylketonuria (PKU), an inherited metabolic disorder, including or PKU) is an inherited metabolic disorder. In PKU disease, the body cannot completely break down the protein phenylalanine because a necessary enzyme mental retardation; seizures; very dry skin ... Read Article

Fragile X Mental Retardation Protein And Synaptic Plasticity
REVIEW Open Access Fragile X mental retardation protein and synaptic plasticity Michael S Sidorov, Benjamin D Auerbach and Mark F Bear* Abstract Loss of the translational repressor FMRP causes Fragile X syndrome. ... Access Full Source

Fragile X Mental Retardation Protein Determinants Required ...
The RNA-binding protein Fragile X Mental Retardation (FMRP) (1,2) is widely expressed in human and mouse tissues and is particularly abundant in the brain (3) due to its high expression ... Doc Viewer

Fragile X Mental Retardation Protein Regulates Trans-synaptic ...
1400 dmm.biologists.org INTRODUCTION Fragile X syndrome (FXS) is caused solely by loss of fragile X mental retardation protein (FMRP), which binds mRNAs to mediate ... Retrieve Document

Author Manuscript NIH Public Access A,b,c, Rachel E ...
Fragile X mental retardation protein levels are decreased in major psychiatric disorders S. Hossein Fatemia,b,c, Rachel E. Kneelanda, Stephanie B. Liescha, and Timothy D. ... Fetch Content

Understanding What Causes Down Syndrome
Down syndrome is caused by having an extra chromosome number 21. But what exactly does this mean? Read this section to learn more about what is known about the cause of Down syndrome, the types of Down syndrome and the relationship between a mother's age and Down syndrome. ... Read Article